Archive for the ‘Virus behavior’ Category
Everybody wants to be sure they know how the Ebola virus infects us. Studies show that skin won’t transfer the virus unless a person’s died of the disease caused by the virus. Casual contact with the Walking Sick — those suffering some of the symptoms such as fever, sore throat, stomach pain, vomiting and diarrhea — probably won’t infect you either. You just have to keep your hands to yourself.
A 2007 study from the Journal of Infectious Diseases took samples from saliva, from semen, sweat and bodily fluids of patients infected with the virus. Scientists were looking for specimens viable enough to grow in a petri dish. One in 12 saliva samples carried the virus. None of the skin swabs tested positive. In semen samples, two of the 38 samples tested positive. The one sweat sample? It tested negative.
The researchers concluded that Ebola transmission via casual contact is a low probability event. Keep in mind that Ebola is not an airborne virus yet, either. So how did the latest person, a doctor in New York City, get infected by the virus? Working with infected patients in Africa. Patients who are emitting blood, or feces via diarrhea, are the most virulent. Even dried blood can remain infectious for over a week.
Where on your body do you get infected? Cuts in your skin, mouth, nose, or eyes. Soft tissue openings always offer a pathway to any virus or bacteria. If someone with active Ebola is still alive, and those pathways of yours are protected, you should be safe. But once a person has died, even their skin carries the virus. Dead bodies, African healthcare duties — there are the elements that contribute to an Ebola infection.
That Journal study was conducted seven years ago. Viruses do mutate, and quickly.
The world’s most deadly virus is infecting our populace with two dangerous diseases: fear and misunderstanding. First comes the misunderstanding. Ebola is not contagious until a person shows symptoms. One of those symptoms is fever, but fever can precede a more commonplace flu.
But people on aircraft who show signs of flu will now be asked to de-board, in some places. Not official policy, just someone being careful. Too much care. Everyone on a flight where an Ebola patient flew — one who had symptoms, but wasn’t detected — will be tested for the virus.
In Texas schools, children who show up with flu have trigged a closing of their schools in the days that follow.
Misunderstanding comes first, and fear follows. Finally, civil rights are removed.
The Ebola virus can only be contracted by contact with bodily fluids. Healthcare workers have elaborate protocols to follow. The CDC is making those protocols more severe. Hospitals don’t have the funding or staff to follow the protocols that are in place. More elaborate protocols will be harder to follow.
Hazmat suits are sold out in major cities in the US. The only people who need a hazmat suit are those in contact with Ebola victims who are fighting the virus. Healthcare workers. But the suits are being purchased by plenty of people who don’t work in healthcare.
Sold out hazmat suits: More evidence of fear, driven by misunderstanding. This is the kind of emotion that drove the Patriot Act, which founded the TSA, which now demands we remove our shoes. Unless the passenger is under 12. Honestly, wouldn’t a dedicated terrorist use a child anyway?
So in response to Ebola fears, airline traffic will decline over the next several months. Smaller airlines, or those in bad financial condition, will struggle when they miss ticket revenues in this busiest of travel seasons. Fear is the most common symptom of a viral infection. It spreads to everyone who does not understand how a virus works, or how to protect ourselves.
Getting a flu shot is more effective than buying a hazmat suit or skipping school or a flight. Last year 52,000 people died in the US due to flu. Ebola has killed one person in the US.
Flu has been with humans for thousands of years, but the rise of arboviruses sparks an era of desperate disease, a battle we are losing. These arboviruses—named after the arthropod mosquitoes, fleas and ticks bearing them—have skipped the virus trademark of preserving a human host. The arboviruses prefer reservoir hosts, birds which don’t catch the virus and only carry it. They enter the bird, whose blood kicks up the virulence a notch. The bird then offers up a more deadly virus to the bug’s next vector, the mosquito. Once a human is infected, the virulence is turned up beyond our natural immunity. This is one spark that heats up the world of 2018, when the trouble begins in Viral Times.
Todd Rider, a scientist at defense-funded Lincoln Laboratories, has moved on from detecting viruses to destroying them. It will be 10 years, by some estimates, before a human version is ready to sell. But a viral pandemic might accelerate that process. Right now he’s testing it on mice. From BusinessWeek:
He describes in the recent journal article a new drug, still under development, which he has successfully used to destroy 15 viral strains, including dengue fever, a stomach virus, and a polio virus. To create it, Rider combined two proteins commonly found in the human body. One binds to viral double-stranded ribonucleic acid, a type of molecule found in all viruses. The other induces apoptosis, which is essentially programmed cell suicide. The drug acts like a homing missile that seeks out and kills cells infected by a virus. It appears to have few negative consequences and works against all diseases, even as they mutate. “Most viruses kill the host cells anyway. They are like aliens in a movie,” says Rider.
Even while a vaccine for H1N1 becomes far more available, doctors are discovering the virus creates infections far deeper in the lungs than seasonal flus.
The pattern of infection among the tiny percentage of people who have died from the virus mirrors the infection methods in the Spanish Flu pandemic of 1918, according to a report on CNN. The story also describes how someone dies from H1N1 infection. Their lungs cease to function well enough to give the victim sufficient air.
“Generally, flu stays in the upper airways,” said Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases. “What this shows is clearly this virus has capability of infecting and causing inflammation and destruction of cells from the trachea, all the way down into smaller cells of the lungs. “The cells of the lung get directly attacked by the virus,” said Fauci.”
Nine out of every 10 people who have died from H1N1 have “underlying conditions” that are pushed into critical status by losing respiratory function. Like a profiler on a CSI episode, the medical community is trying to match conditions to deaths. 72 percent of those who have died had obesity in their profile.
Vanderbilt University researcher Dr. William Schaffner, professor in the Division of Infectious Diseases at the university’s School of Medicine, was surprised by the H1N1 fatality-obesity connection.
“That was a striking finding,” said Schaffner. “It contributes in a very material way to what we know about risks for a severe outcome with H1N1 infection. We are keeping an eye on obesity as a risk factor for H1N1 death.”